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A New Nervogenic Acid Glycoside with Pro-coagulant Activity from Liparis Nervosa

Year: 2013

Type: article

Abstract: In an effort to identify hemostatic components from Liparis nervosa (Thunb.) Lindl. using a bioactivity-guided fractionation approach, the n-BuOH extract was found to promote ADP-induced platelet aggregation and two compounds were isolated from the active extract. Compound 1 was a new nervogenic acid glycoside and the structure was elucidated as 3,5-bis(3-methyl-but-2-enyl)-4-O-[beta-D-xylopyranosyl-(1 -->2)-beta-D-glucopyranosyl]-benzoic acid by extensive spectroscopic measurements. Adenosine (2) was isolated from this plant for the first time. Compound 1 also showed good pro-coagulant activity in vitro.

Source: Natural Product Communications

DOI: 10.1177/1934578x1300800821

Authors: Qin Song, Qingyao Shou, Xiaojun Gou, Fengzhen Chen, Jing Leng, Weifeng Yang

Institutions: Chengdu University, Southern Cross University, Hubei University of Chinese Medicine

Language: English

Topic: Phytochemistry and Biological Activities

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W31130731

FWCI: 0.724

Cites: 2

Cited by: 6

Related to: 10