Work

Anti-polyphenol oxidase properties of total flavonoids from young loquat fruits: inhibitory activity and mechanism

Year: 2021

Type: article

Abstract: This study investigated anti-polyphenol oxidase activity and mechanism of purified total flavonoids (PTF) from young loquat fruits. PTF remarkably inhibited the activity of polyphenol oxidase (PPO) with an IC50 value of 21.03 ± 2.37 μg/mL. Based on enzyme kinetics, PTF was found to be a potent, mixed-type, and reversible inhibitor of PPO. The fluorescence intensity of PPO was quenched by PTF through forming a PTF-PPO complex in a static procedure. Therefore, this study authenticated PTF as an efficient PPO inhibitor, which would contribute to their utilization in food industry.

Source: Bioengineered

DOI: 10.1080/21655979.2021.1886387

Authors: Gui-Li Huang, Ling-Xiang Sun, Jia-Jia Ma, Si-Yao Sui, Yu-Ning Wang

Institutions: Suzhou Academy of Agricultural Sciences, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry

Language: English

Topic: Phytochemicals and Antioxidant Activities

Subfield: Biochemistry (medical)

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $2,864

Funder: Jiangsu Province Biomass Energy and Material Laboratory