Deciphering the autophagy regulatory network via single-cell transcriptome analysis reveals a requirement for autophagy homeostasis in spermatogenesis
Year: 2021
Type: article
Abstract: Our study provides comprehensive insights into the global transcriptional signatures of autophagy-related genes and confirms the importance of autophagy homeostasis in SSC maintenance and normal spermatogenesis, opening new avenues for further dissecting the significance of the autophagy regulatory network in spermatogenesis as well as male infertility.
Source: Theranostics
DOI: 10.7150/thno.55645
Institutions: Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Southern Medical University, Jinan University, Zhuhai People's Hospital, Nanfang Hospital, Shenzhen University Health Science Center, Third Affiliated Hospital of Guangzhou Medical University, Chinese Academy of Sciences, Beijing Institute of Genomics, University of Macau, Zhujiang Hospital
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,671
OpenAlex ID: W3136405263