Comparison of the Effects of Isoflurane and Sevoflurane on BAER and Tympanometry in Dogo Argentino Breed Puppies
Year: 2021
Type: article
Abstract: Isoflurane and sevoflurane are the most frequently used volatile anesthetic agents in veterinary practice yet their effects on the brain are not fully understood.In this study, it was aimed to compare the brainstem auditory evoked response (BAER) test data recorded during stable general anesthesia periods in specific MAC (Minimal Alveolar Concentration) values of sevoflurane (1.7%) and isoflurane (2.1%).The patients who were evaluated as healthy according to physical, videootoscopy, and tympanometry examination results were included in the study.Thus, detailed breed specific reference tympanometric values were obtained in a certain age range.In the study, 12 (9 male and 3 female) Dogo Argentino breed, 8-12 weeks old, healthy dogs were used, which were maintained with anesthesia with isoflurane (n: 6) and sevoflurane (n: 6).As well as tympanometry data, the latency, amplitude, V/I amplitude ratio, and interpeak latencies between the two groups BAER records were compared.Data were analyzed using Student's t-test.Statistical significance was determined as P<0.05.The study design is prospective, clinical, blind, cross-study.In conclusion, the brain appears to be more suppressed for the minimal alveolar concentration values determined in this study in the isoflurane group, but tympanometry values were not affected.
Source: DergiPark (Istanbul University)
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3163376894