Work

HIF-1-induced mitochondrial ribosome protein L52: a mechanism for breast cancer cellular adaptation and metastatic initiation in response to hypoxia

Year: 2021

Type: article

Abstract: This work elucidates the molecular mechanism by which MRPL52 mediates hypoxia-induced apoptotic resistance and metastatic initiation of breast cancer, and provides new insights into the interplay between cancer and the tumor microenvironment.

Source: Theranostics

DOI: 10.7150/thno.57804

Authors: Xinyan Li, Mengshen Wang, Su Li, Yuqiong Chen, Mozhi Wang, Zhonghua Wu, Xiangyu Sun, Litong Yao, Haoran Dong, Yongxi Song, Yingying Xu

Institutions: First Hospital of China Medical University, Fudan University, Zhongshan Hospital

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,671

Funders: National Natural Science Foundation of China, China Medical University

Award: G6699698825

OpenAlex ID: W3172823398

FWCI: 3.353

Cites: 93

Cited by: 68

Related to: 9