Work

CD8 + T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19

Year: 2021

Type: article

Abstract: T cells with these conserved specificities are much more abundant in COVID-19 patients with mild disease versus those with a more severe illness, suggesting a protective role.

Source: Science Immunology

DOI: 10.1126/sciimmunol.abg5669

Authors: Vamsee Mallajosyula, Conner Ganjavi, Saborni Chakraborty, Alana M. McSween, Ana Jimena Pavlovitch-Bedzyk, Julie Wilhelmy, Allison Nau, Monali Manohar, Kari C. Nadeau, Mark M. Davis

Institutions: Stanford Medicine, Stanford University, Howard Hughes Medical Institute

Language: English

Topic: SARS-CoV-2 and COVID-19 Research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Howard Hughes Medical Institute, Bill and Melinda Gates Foundation, International Team for Implantology, National Institutes of Health, Sean N. Parker Center for Allergy and Asthma Research, Stanford University, National Institute of Allergy and Infectious Diseases

Awards: G1055462175, G1699415091, G248838502, G73616645, G9000095646, Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro

OpenAlex ID: W3175436048

FWCI: 9.46

Cites: 66

Cited by: 164

Related to: 10