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Selection of CHO host and recombinant cell pools by inhibition of the proteasome results in enhanced product yields and cell specific productivity

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Year: 2021
Type: article
Source: Journal of Biotechnology
DOI: 10.1016/j.jbiotec.2021.06.019
Authors: Tanya J. Knight, Sarah Turner, Colin M. Jaques, C. Mark Smales
Institutions: University of Kent, Lonza (United Kingdom)
Language: English

Topic: Viral Infectious Diseases and Gene Expression in Insects
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: UK Research and Innovation, Biotechnology and Biological Sciences Research Council, Innovate UK
Awards: G1774008122, G8130791949, Translation of Step-changing Bioprocesses and Expression System Technologies for Next Generation Protein Biologics Production in CHO Cells
OpenAlex ID: W3175572973
FWCI: 0.701
Cites: 42
Cited by: 14
Related to: 10
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