Towards More Predictive, Physiological and Animal-free In Vitro Models: Advances in Cell and Tissue Culture 2020 Conference Proceedings
Year: 2021
Type: article
Abstract: Experimental systems that faithfully replicate human physiology at cellular, tissue and organ level are crucial to the development of efficacious and safe therapies with high success rates and low cost. The development of such systems is challenging and requires skills, expertise and inputs from a diverse range of experts, such as biologists, physicists, engineers, clinicians and regulatory bodies. Kirkstall Limited, a biotechnology company based in York, UK, organised the annual conference, Advances in Cell and Tissue Culture (ACTC), which brought together people having a variety of expertise and interests, to present and discuss the latest developments in the field of cell and tissue culture and in vitro modelling. The conference has also been influential in engaging animal welfare organisations in the promotion of research, collaborative projects and funding opportunities. This report describes the proceedings of the latest ACTC conference, which was held virtually on 30th September and 1st October 2020, and included sessions on in vitro models in the following areas: advanced skin and respiratory models, neurological disease, cancer research, advanced models including 3-D, fluid flow and co-cultures, diabetes and other age-related disorders, and animal-free research. The roundtable session on the second day was very interactive and drew huge interest, with intriguing discussion taking place among all participants on the theme of replacement of animal models of disease.
Authors: Bhumika Singh, Mohamed Essameldin Abdelgawad, Zulfiqur Ali, Jarrod Bailey, Elisa Budyn, Prospero Civita, Martin J.D. Clift, John T. Connelly, Samuel Constant, Marius Hittinger, Helena Kandarova, Victoria Rosalind Kearns, Tony Kiuru, Tomasz Kostrzewski, Sebastian Kress, Victoria Marsh Durban, Claus-Michael Lehr, Hayley McMillan, Julia Katharina Metz, Vivian Monteban, Dania Movia, Catia Neto, Carla Owen, Lauri Paasonen, Kerri Anne Palmer, Geoffrey John Pilkington, Karen Pilkington, Adriele Prina-Mello, Clive Roper, Jonathan Sheard, Sheree Smith, Janette Ellen Turner, Ipsita Roy, Melissa Anne Tutty, Eirini Velliou, John Malcolm Wilkinson
Institutions: Kirkstall (United Kingdom), Helwan University, Teesside University, École Normale Supérieure Paris-Saclay, Centre National de la Recherche Scientifique, Université Paris-Saclay, University of Portsmouth, Cardiff University, Swansea University, Queen Mary University of London, Blizard Institute, Slovak Academy of Sciences, Centre of Experimental Medicine of the Slovak Academy of Sciences, University of Liverpool, UPM (Finland), CN Bio Innovations (United Kingdom), BOKU University, Helmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland, Saarland University, Queen's University Belfast, Trinity College Dublin, Animal Free Research UK, University of Aberdeen, Leeds Beckett University, University of Sheffield, University College London
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3181925474