A study on the esophageal dynamics in patients with gastroesophageal reflux disease and with refractory cough undergoing esophageal high-resolution manometry.
Year: 2021
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: To analyze the esophageal dynamics in patients with gastroesophageal reflux disease (GERD) and with refractory cough while undergoing esophageal high-resolution manometry (HRM). METHODS: A total of 32 patients with GERD and with refractory cough and 48 patients with GERD admitted to our hospital from February 2019 to July 2020 were assigned to the combined group and the GERD group, respectively, and 40 healthy volunteers were assigned to the healthy group. All the patients underwent HRM. The lower esophageal sphincter (LES) and the upper esophageal sphincter (UES) parameters, the types of peristalsis of the esophageal body, the esophageal body motility, the i relaxation of LES and UES incidence rates, and the esophageal body motility disorders were compared among the three groups. RESULTS: < 0.05). CONCLUSION: Patients with GERD and with refractory cough often also have esophageal body motility disorders, longer PB, elevated UESP levels, and lower DCI. HRM can be used to objectively evaluate the esophageal dynamics and to differentiate among diseases.
Source: Europe PMC (PubMed Central)
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3199416640