Year: 2021
Type: article
Study design: Observational Study
Abstract: Objectives: Clinical features and risk factors are highly variable for Coronavirus disease-2019 .Researchers investigate for the prediction of people who have high risk of developing severe illness and dying.The aim of this study is to examine the effect of obesity on the course of COVID-19. Materials and Methods:Patients with laboratory confirmed COVID-19 were retrospectively screened between March 11 and April 30.Anthropometric measures including standing height and body weight were measured at admission.Body mass index (BMI) was calculated and patients were classified into three groups as BMI<25, BMI 25-29.99,and BMI≥30 according to the guidelines for the diagnosis and treatment of obesity in Turkey.Results: A statistically significant correlation was found between BMI and disease severity and intensive care unit admission (p<0.001andp<0.001 respectively).A significant relationship was found between the BMI and support of invasive mechanical ventilation (p=0.007).Mortality rates of the patients were also significantly different in BMI groups (p=0.030).The mortality rate was 1.1% in patients with a BMI <25 and 1.3% in patients with a BMI 25-29.99.However, mortality rate was 8.6% in patients with a BMI ≥30. Conclusion:The relationship between infectious diseases and obesity has not been established yet.Immune system deficiency, obesity-related comorbidities and respiratory tract abnormalities may cause poor prognosis of infectious diseases.So early detection and aggressive treatment for obese patient with COVID-19 is very important.
Institution: Ankara Yıldırım Beyazıt University
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W3201599345