Harnessing novel engineered feeder cells expressing activating molecules for optimal expansion of NK cells with potent antitumor activity
Year: 2021
Type: article
Abstract: Natural killer (NK) cells play an important role in the antitumor immune response as the major cytotoxic lymphocytes in the innate immune system. NK cells without any genetic modifications have been used for both autologous and allogeneic therapies. Moreover, many reports have suggested that allogeneic NK cells can reduce the recurrence of disease and improve survival through a graft-versus-leukemia effect without GVHD [ 1 , 2 ].
Institution: Korea Advanced Institute of Science and Technology
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $4,480
OpenAlex ID: W3202869559