Work

Phenytoin toxicity presenting with acute visual loss and acute delirium, a case report

Year: 2018

Type: article

Abstract: Phenytoin is a widely prescribed antiepileptic agent for both focal and generalized seizure. We report a case of a 20-year-old man with focal epilepsy presented with acute bilateral visual loss, and delirium. His random phenytoin serum concentration on admission was 43.6 mg/L, well above the recommended therapeutic range of 10-20 mg/L. Extensive investigations have ruled out other vascular or demyelinating causes. His visual symptoms completely resolved after discontinuing phenytoin for 84 hours. This case shows that acute phenytoin toxicity can result in reversible visual failure.

Source: The University of Malaya Research Repository (University of Malaya)

Authors: Sin Hong Chew, Irene Looi, Yoke‐Lin Lo, Kheng Seang Lim

Language: English

Topic: Epilepsy research and treatment

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3203299178

FWCI: 0.164

Cites:

Cited by: 2

Related to: 10