Edaravone Combined with Clopidogrel Is Beneficial to Improve Efficacy, Neurological Impairment, and Life Function in Acute Cerebral Infarction Patients

Year: 2021

Type: article

Abstract: OBJECTIVE: This research aimed at investigating the efficacy of edaravone combined with clopidogrel on acute cerebral infarction (ACI) and its influence on the neurological deficit and life function. METHODS: = 83) according to the treatment methods. Patients in the CG were treated with clopidogrel alone, and those in the RG were under edaravone-clopidogrel combination therapy. The efficacy, adverse reactions, NIHSS score, cerebral hemodynamic indexes, and Fugl-Meyer scale (FMA) and Barthel index (BI) of activities of daily living (ADL) scores were observed. RESULTS: Compared with before treatment, the symptoms of both groups were improved after treatment: the NIHSS scores decreased, FMA and ADL scores increased, and cerebral hemodynamic indexes were improved. Compared with the CG, the efficacy and cerebral hemodynamic indexes of the RG were better, the adverse reactions were equivalent, the NIHSS score was lower, and the ADL and FMA scores were higher. CONCLUSION: Edaravone combined with clopidogrel can effectively treat ACI and improve the neurological deficit and life function of patients.

Source: Evidence-based Complementary and Alternative Medicine

DOI: 10.1155/2021/8030521

Authors: Liao Wu, Ying Sun, Guihua Ni, Bo Sun, Xiaoyu Ni, Shikun Cai

Institution: Huaian First People’s Hospital

Language: English

Topic: Acute Ischemic Stroke Management

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,550