Prevention and Treatment of SARS-CoV2 Infection in People Living with HIV: The Need for Specific Data
Year: 2021
Type: article
Abstract: The HIV pandemic has led to close to 40 million people living with HIV (PLWH) worldwide. To date, SARS-CoV2 has affected > 220 million people, and unprecedented global efforts have resulted in almost 6000 million doses of SARS-CoV2 vaccines being administered. Although several specific COVID-19 antiviral and anti-inflammatory treatments and SARS-CoV2 vaccines have been approved, the data available to support their use in specific populations such as PLWH remain limited. PLWH includes a range of individuals from practically unaffected immunity to severely immunocompromised individuals, and preventive and therapeutic interventions should be tailored for these subgroups . However, in most randomized clinical trials regarding antivirals, immunomodulators and vaccines for COVID-19, PLWH have been excluded or only enrolled in small numbers leading to a paucity of data. We briefly discuss the current evidence for prevention and treatment of COVID-19 in PLWH and identify key areas where more information is required.
Source: Infectious Diseases and Therapy
Authors: Natalia A. Díaz, Rosa de Miguel, Fernando Agüero, Omar Sued, José R. Arribas, Juan Ambrosioni, Juan Ambrosioni, José L. Blanco, Lorena de la Mora, Felipe García-Alcaide, Ana González-Cordón, Alexis Inciarte, Montserrat Laguno, Lorna Leal, Esteban Martínez-Chamorro, María Martínez-Rebollar, José M. Miró, Jhon F. Rojas, Berta Torres, Josep Mallolas, Laia Albiac, Daiana L. Agüero, Marta Bodro, Celia Cardozo, Mariana Chumbita, Nicol García, Carolina García-Vidal, Marta M. Hernández-Meneses, Sabina Herrera, Laura Linares, Antonio Moreno, Laura Morata, Jose A. Martínez-Martínez, Pedro Puerta, Verónica Rico, Alex Soriano, Mikel Martínez, María del Mar Mosquera, María A. Marcos, Jordi Vila, Montse Tuset, Dolors Soy, Anna Vilella, Alex Almuedo, María J. Pinazo, José Muñoz
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $6,000
OpenAlex ID: W3208900375