Hipocolesterolemia en el paciente quemado
Year: 2017
Type: article
Abstract: Cholesterol is a biomolecule that fulfills important structural, metabolic and physiological functions. It is an essential component of cell membranes (cytoplasmic, nuclear and organelles). It functions as an antioxidant, is a precursor of serotonin, bile salts, steroid hormones (adrenal cortex hormones, glucocorticoids and mineralocorticoids) and sex hormones. Vitamin D is also an important cholesterol derivative. In the case of the burned patient, hypocholesterolemia has a multifactorial origin. Evidence suggests that elevation of cytokines occurring during the systemic inflammatory response is responsible for the rapid and noticeable decrease in plasma cholesterol concentration. In the burned patient, both cholesterol needs and catabolism are increased. For all of the above, the behavior of cholesterol in burnt patients could be considered as an adaptive response to trauma, but the decrease to certain levels may cause undesirable effects on the evolution and results. This review seeks to know the biochemical, physiological and metabolic elements of this molecule, surrounded by numerous myths that do not recognize its true meaning for life, health and the emergence of acute and chronic diseases.
Source: Acta Médica
Language: Spanish
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W3210076791