A Review on Self Nano Emulsifying Drug Delivery System
Year: 2019
Type: article
Abstract: A self-nano emulsifying drug delivery system (SNEDDS) is a scheme of drug delivery that utilizes a chemical rather than a mechanical method of Nano emulsion . That is, by an intrinsic property of the drug formulation. It utilizes the familiar ouzo impact shown by anethole in many anise-flavored liquors, rather than by unique blending and handling Nano emulsion s have significant potential for use in the delivery of drugs, and SNEDDS (including so-called "U-type" nano emulsions) is the best of those systems to date identified. SNEDDS are of particular value in increasing the absorption of lipophilic drugs taken by mouth. For oral use, SNEDDS can be formulated as liquids or solids, as solids contained in capsules or tablets. Limited studies compared these reports that SNEDDS is superior to solid SNEDDS in terms of bioavailability, which are superior to conventional tablets. Liquid SNEDDS also displayed the value in injectable formulations (IV and urethral) and in a topical (oral) spray. The SNEDDS (Self-nano emulsifying drug delivery system) is a significant application for BCS Class II and Class IV drugs for water improvement Solubility of drugs that are not water-soluble. Preventing interfacial tension and enhancing dissolution as well as drug molecule absorption rate is essential.
Authors: M Mounika, Prasanna Kumar Desu, K Vanitha
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W3210099403