The barley immune receptor Mla recognizes multiple pathogens and contributes to host range dynamics
Year: 2021
Type: article
Abstract: Crop losses caused by plant pathogens are a primary threat to stable food production. Stripe rust (Puccinia striiformis) is a fungal pathogen of cereal crops that causes significant, persistent yield loss. Stripe rust exhibits host species specificity, with lineages that have adapted to infect wheat and barley. While wheat stripe rust and barley stripe rust are commonly restricted to their corresponding hosts, the genes underlying this host specificity remain unknown. Here, we show that three resistance genes, Rps6, Rps7, and Rps8, contribute to immunity in barley to wheat stripe rust. Rps7 cosegregates with barley powdery mildew resistance at the Mla locus. Using transgenic complementation of different Mla alleles, we confirm allele-specific recognition of wheat stripe rust by Mla. Our results show that major resistance genes contribute to the host species specificity of wheat stripe rust on barley and that a shared genetic architecture underlies resistance to the adapted pathogen barley powdery mildew and non-adapted pathogen wheat stripe rust.
Source: Nature Communications
Authors: Jan Bettgenhaeuser, Inmaculada Hernández-Pinzón, Andrew M. Dawson, Matthew Gardiner, Phon Green, Jodie Taylor, Matthew Smoker, John N. Ferguson, Peter Emmrich, Amelia Hubbard, Rosemary Bayles, Robbie Waugh, Brian J. Steffenson, Brande B. H. Wulff, Antonín Dreiseitl, Eric R. Ward, Matthew J. Moscou
Institutions: University of East Anglia, Norwich Research Park, Sainsbury Laboratory, KWS Saat (Germany), University of Cambridge, John Innes Centre, National Institute of Agricultural Botany, James Hutton Institute, University of Minnesota, King Abdullah University of Science and Technology, Agrotest Fyto (Czechia), AgBiome (United States)
Language: English
Subfield: Plant Science
Domain: Life Sciences
SDG: Zero hunger
Open Access status: gold
Estimated APC paid: $5,560
OpenAlex ID: W3216631842