Hematology parameters in dogs treated with subconjunctival application of limbal stem cells allografts
Year: 2015
Type: article
Abstract: The cornea, as a source for obtaining stem cells, is a good medium for their use in veterinary ophthalmology.In this research, we used dogs which had been diagnosed with extensive, chronic thinning of the central cornea (vertex corneae) generated due to complicated mechanical damage to the corneae pannosa.The goal of this study was to test whether subconjuctival application of limbal stem cells allografts had any infl uence on haematology parameters in peripheral blood.The animals were divided into three experimental groups regardless of breed, sex and age, and each group comprised 7 dogs.Group A consisted of clinically healthy dogs (control), in group B there were dogs who had had injuries treated by a conventional ophthalmological approach in veterinary medicine, and group C in which corneal injuries were treated using subconjuctival cell allografts.Blood samples were taken four times during the experiment from all animals for haematological analysis.Transplantation of limbal stem cell allografts did not affect the physiological haematology parameters.
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Sveučilište u Zagrebu
OpenAlex ID: W323348154