Phylogenic Analysis of Echovirus Type 30 Isolated from a Large Epidemic of Aseptic Meningitis in Japan during 1997-1998
Year: 1999
Type: article
Abstract: During 1997 to 1998, a nationwide epidemic of aseptic meningitis occurred in Japan. More than 4,500 isolates from patients with aseptic meningitis were identified as echovirus type 30. To investigate the character of these isolates, we examined the nucleotide sequences of thirty-seven geographical representatives and compared them with 50 strains isolated during the past 20 years. The phylogenic analysis used partial sequences from either the VP1 or VP4-VP2 region of the viral capsid. This analysis revealed that the isolates were divided into six genomic groups. All isolates identified during 1997-1998 belonged to only two genomic groups; these two groups are thought to be the causative viral agents involved in the recent epidemic.
DOI: 10.7883/yoken.52.160
Authors: Hiromu Yoshida, Zheng Hong, Tetsuo Yoneyama, Kumiko Yoshii, Hiroyuki Shimizu, Kozo Ota, Tsukasa Murakami, Nobuhiro Iritani, Misako Tsuchiya, Shinichi Takao, Kazue Uchida, Shigeki Yamanishi, Mitsuhiro Hamazaki, Shuji Yoshino, Mitsuaki Oseto, Katsuhiko Abe, Masako Hamano, Kenji Sakae, Hideaki Tsuzuki, Seizo Chiya, Hajime Onishi, Tsuguto Fujimoto, Tetsuya Munemura, Ayumi Kawamoto, Yoko Yokota, Shuji Ando, Hiromasa Sekine, Masayuki Akami, Setsuko Iizuka, Akio Hagiwara, Tatsuo Miyamura
Institutions: National Institute of Infectious Diseases, Fukuoka City Institute of Health and Environment, Saitama Prefectural Institute of Public Health, Fukuoka Institute of Health and Environmental Sciences, Miyazaki Prefectural Institute for Public Health and Environment, Ehime Prefectural Institute of Public Health and Environmental Science, Hiroshima City Institute of Public Health, Okayama Prefectural Institute for Environmental Science and Public Health, Aichi Prefectural Institute of Public Health, Ishikawa Prefectural Institute of Public Health and Environmental Science, Hyogo Prefectural Institute of Environmental Sciences, Yokohama City Institute of Public Health, Shiga Prefectural Institute of Public Health, Toyama Institute of Health, Tokyo Metropolitan Institute of Public Health, Gunma Prefectural Institute of Public Health and Environmental Sciences, Shimane Prefectural Institute of Public Health and Environmental Sciences
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W340087073