A comparison of the effects of 6-hydroxydopamine and reserpine on noradrenergic and peptidergic nerves in rat brown adipose tissue.
Year: 1989
Type: article
Abstract: While co-existence of noradrenaline and neuropeptide-Y is, by inference, indicated in sympathetic nervous projections to rat interscapular brown adipose tissue by the fact of their coincident disappearance from the tissue following 6-hydroxydopamine treatment of the animals, reserpine treatment produced a divergent effect suggestive of possible differences either in the localisation and/or release mechanisms for noradrenaline and the peptide within the same neurons. Thus reserpine produced a depletion of noradrenaline but not of the immunohistochemically demonstrable neuropeptide-Y in the nerve plexuses of the tissue.
Source: Europe PMC (PubMed Central)
Authors: S Mukherjee, J D Lever, D Norman, D Symons, T L Spriggs, R T Jung
Institution: University of Wales
Language: English
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W344602168