Work

Room-temperature Suzuki-Miyaura reactions mediated by native and derivatized b−cyclodextrins

Year: 2013

Type: conference-paper

Abstract: Suzuki-Miyaura reactions provide a simple and effective synthetic route to biaryls by using a wide range of palladium catalysts. Our group has recently showed that 2-hydroxypropyl-_-cyclodextrin is an effective green reductant/capping agent for the preparation of Pd nanoparticles with good catalytic activity in C-C cross-couplings in water. In this work, we present our findings concerning the effect of different _-CDs on the room-temperature Suzuki- Miyaura reaction between phenylboronic acid and 4- bromoacetophenone in the isopropyl alcohol-water system. The results suggest that the nature of the substituents and CD concentration play a role in the catalysis.

Source: Brazilian Meeting on Organic Synthesis (BMOS)

DOI: 10.5151/chempro-14bmos-r0021-1

Authors: Aires da Conceição Silva, Jaqueline D. Senra, Lúcia C. S. Aguiar, Alessandro B. C. Simas, Andréa Luzia F. de Souza, Luiz Fernando B. Malta

Institution: Universidade Federal do Rio de Janeiro

Language: English

Topic: Catalytic Cross-Coupling Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funders: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro, Universidade Federal do Rio de Janeiro

OpenAlex ID: W35443384