High level transferable resistance among Escherichia coli
Year: 1994
Type: article
Abstract: Escherichia coli strains (48) isolated from clinical cases of man and animals were screened for their antibiotic resistance profile and their potential to exchange their chromosomal chromosomal genetic materials (R-plasmids). Of these 32 (66.66%) strains were resistant to one or more drugs. Multiple resistance was observed in 26 (81.56%) strains. Maximum number of strains were resistant to streptomycin (64.41%) followed by ampicillin (56.25%). tetracycline (52.83%). amoxycillin (50%). chloramphenicol (41.66%) and co-trimoxazole (37.31%), and least to kanamycin (10.41 %), nitrofurantoin and nitrofurazone (8.33% each). None of the strans were resistant to nalidixic acid: 13 multi-resistant strams could transfer their drug resistance markers to the recipient E. coli K 12 J 62-1. These transferred R-factors were stable for several generations. Strains possessing single. double or triple drug-resistant markers were mostly non-transferable by conjugation experiments in vitro.
Authors: Iqbal Ahmad, J. N. S. Yadava, Shamim Ahmad
Language: English
Subfield: Molecular Medicine
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W354978950