Year: 1994
Type: article
Study design: Case Report
Abstract: Toshihiko SAKAI2), Nobuki SAKAGUCHI2) Toshitsugu NAKAMURA3) and Masao HOTCHI2) 1) StZtdentsげSleinshu乙「nivers吻SchoolげMedicine 2) 1)ePartment(ゾPathology， Shinshzaひnivers勿S魏oo♂げMedicin召 3) DePartment(ゾPathology， Suwa 1-edα oss正lospitalArare case of multip王e endocrine neoplasia(MEN， type I)associated with gastric carcinoid， adrenQcor・ tical hyperplasia and meningioma was reported． A54-year-old woman who had suffered from leg pain for several years was found to be hypercalcemic and a工arge mass was discovered in the right side of her neck． An emergency operation for parathyroidectQmy was perfonned because of the marked hypercalcemia， but she died soon after surgery． The resected parathyroid tumor as well as three other glands showed the histological features of chief cell adenoma． In addition， autopsy revealed chromophobe adenoma of the anterior lobe of the pituitary gland， multiple minute adenomas of the pancreatic islets， gastric carcinoid and multiple hyperplastic nodules of the adrenal cortices． She also had a menin奮ioma on the cerebellar vermis． The combination patterns of type 1 MEN and other neuroendocrine tumors as well as their genetic abnormalities were discussed together with the literature． Shinslau Med ／42：6LZ-67，1994
Language: Japanese
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W398304002