Work

4-(4-Amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate

Year: 2012

Type: article

Abstract: In the title compound, C(15)H(12)FN(3)O(3)·CH(3)OH, the dihedral angle between the quinazoline ring system and the benzene ring is 81.18 (9)°. In the crystal, mol-ecules are linked by N-H⋯O and O-H⋯N hydrogen bonds, generating [10-1] chains of alternating main mol-ecules and solvent mol-ecules. Weak C-H⋯O inter-actions are also observed.

Source: Acta Crystallographica Section E Structure Reports Online

DOI: 10.1107/s1600536812011725

Authors: Wei Huang, Aimin Tan

Institutions: Simcere Pharmaceutical (China), State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University

Language: English

Topic: Crystal structures of chemical compounds

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $500

OpenAlex ID: W40851936