Work

A Vanishing Cecal Mass: A Rare Gastrointestinal Manifestation of Systemic Mastocytosis

Year: 2021

Type: article

Abstract: Systemic mastocytosis (SM) is a heterogeneous disease that often involves the gastrointestinal (GI) tract. Activation and accumulation of mast cells in GI organs can result in symptoms of abdominal pain, nausea and diarrhea along with organ damage with more aggressive disease. Mast cell degranulation can also result in anaphylactic reactions, which can be life-threatening. Recognition of GI manifestations is important for gastroenterologists to aid in diagnosis and management when GI involvement is suspected. Edema, small nodules, urticarial lesions and occasionally ulceration in the small bowel and colon are the most commonly described endoscopic findings. Here we describe a case of SM presenting as a large colonic mass and provide a brief review of the literature on GI involvement of SM.

Source: Cureus

DOI: 10.7759/cureus.20784

Authors: Krista Newman, Gregory Vercellotti, Dale Snover, Timothy Peterson, Eugenia Shmidt

Institution: University of Minnesota

Language: English

Topic: Mast cells and histamine

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4200112121