Clinicians for CARE: A Systematic Review and Meta‐Analysis of Interventions to Support Caregivers of Patients With Heart Disease
Year: 2021
Type: review
Study designs: Systematic Review, Meta-Analysis
Abstract: Background Caregivers provide critical support for patients with chronic diseases, including heart disease, but often experience caregiver stress that negatively impacts their health, quality of life, and patient outcomes. We aimed to inform health care teams on an evidence-based approach to supporting the caregivers of patients with heart disease. Methods and Results We conducted a systematic review and meta-analysis of randomized controlled trials written in English that evaluated interventions to support caregivers of patients with heart disease. We identified 15,561 articles as of April 2, 2020 from 6 databases; of which 20 unique randomized controlled trials were evaluated, representing a total of 1570 patients and 1776 caregivers. Most interventions focused on improving quality of life, and reducing burden, depression, and anxiety; 85% (17 of 20) of the randomized controlled trials provided psychoeducation for caregivers. Interventions had mixed results, with moderate non-significant effects observed for depression (Hedges' g=-0.64; 95% CI, -1.34 to 0.06) and burden (Hedges' g=-0.51; 95% CI, -2.71 to 1.70) at 2 to 4 months postintervention and small non-significant effects observed for quality of life and anxiety. These results were limited by the heterogeneity of outcome measures and intervention delivery methods. A qualitative synthesis of major themes of the interventions resulted in clinical recommendations represented with the acronym "CARE" (Caregiver-Centered, Active engagement, Reinforcement, Education). Conclusions This systematic review highlights the need for greater understanding of the challenges faced by caregivers and the development of guidelines to help clinicians address those challenges. More research is necessary to develop clinical interventions that consistently improve caregiver outcomes.
Authors: Kellen A. Knowles, Helen Xun, Sunyoung Jang, Sharon Pang, Charles Ng, Apurva Sharma, Erin M. Spaulding, Rohanit Singh, Alaa Diab, Ngozi Osuji, Joshua Materi, Danielle Amundsen, Shannon Wongvibulsin, Daniel Weng, Pauline Huynh, Julie Nanavati, Jennifer Wolff, Francoise A. Marvel, Seth S. Martin
Language: English
Topic: Nursing care and research
Subfield: Pharmacy
Field: Health Professions
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,025
Funders: Aetna Foundation, American Heart Association, Amgen, Johns Hopkins University, National Institutes of Health, Johns Hopkins Bloomberg School of Public Health, National Heart, Lung, and Blood Institute, National Institute of Nursing Research, National Institute of General Medical Sciences, National Center for Advancing Translational Sciences
Awards: Medical Scientist Training Program, Sudden Cardiac Arrest (SCA): Prediction and Prevention, Interdisciplinary Training in Cardiovascular Health Research, Hormonal, Metabolic and Signaling Interactions in PAH, The Process of User Engagement with mHealth, Johns Hopkins Institute for Clinical and Translational Research, Cardiovascular Epidemiology Institutional Training
OpenAlex ID: W4200325837