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T-cells of invasive candidiasis patients show patterns of T-cell-exhaustion suggesting checkpoint blockade as treatment option

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Year: 2021
Type: article
Study design: Observational Study
Source: Journal of Infection
DOI: 10.1016/j.jinf.2021.12.009
Authors: Sibylle C. Mellinghoff, Martin Thelen, Christiane Bruns, Maria Garcia-Marquez, Pia Hartmann, Tatjana Lammertz, Jonas Lehmann, Angela Nowag, Jannik Stemler, Kerstin Wennhold, Oliver A. Cornely, Michael S. von Bergwelt-Baildon, Hans A. Schlößer
Institutions: University of Cologne, German Center for Infection Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, University Hospital Cologne, Laboratory Dr. Wisplinghoff, LMU Klinikum, Deutsches Konsortium für Translationale Krebsforschung, Ludwig-Maximilians-Universität München
Language: English

Topic: Antifungal resistance and susceptibility
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Deutsche Forschungsgemeinschaft, Universität zu Köln, Universitätsklinikum Köln
Awards: G1116613410, Tumorspezifische endogene Immunantwort bei ösophagogastralen Adenokarzinomen.
OpenAlex ID: W4200513209
FWCI: 1.531
Cites: 31
Cited by: 33
Related to: 10
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