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Pirfenidone attenuates acetaminophen-induced liver injury via suppressing c-Jun N-terminal kinase phosphorylation

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Year: 2021
Type: article
Source: Toxicology and Applied Pharmacology
DOI: 10.1016/j.taap.2021.115817
Authors: Shigeki Tashiro, Masatake Tanaka, Takeshi Goya, Tomomi Aoyagi, Miho Kurokawa, Koji Imoto, Akifumi Kuwano, Motoi Takahashi, Hideo Suzuki, Motoyuki Kohjima, Masaki Kato, Yoshihiro Ogawa
Institutions: Kyushu University, Nakamura Gakuen University
Language: English

Topic: Drug-Induced Hepatotoxicity and Protection
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: Takeda Science Foundation, Smoking Research Foundation, Japan Society for the Promotion of Science
Awards: G1608315289, G1647740241, The resesarch on platicity and heterogeneity of hepatocyte in acute liver injury, Elucidation of the mechanism of non-alcoholic steatohepatitis focusing on the metabolic zonation in the liver., Development and progression mechanism of NASH from the viewpoint of cell-cell interaction and medical application, The change of glucose and lipid metabolism in hepatocellular carcinoma and the involvement to tumor dedifferntiation, G6312633290, The effect of smoking on hepatocyte plasticity and heterogeneity in liver failure, G877852359
OpenAlex ID: W4200545780
FWCI: 1.915
Cites: 68
Cited by: 16
Related to: 10
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