Year: 2021
Type: article
Abstract: Diosgenin is a steroidal saponin isolated from dioscorea opposita, which has been proven to have anti-cancer, anti-inflammatory, anti-thrombotic and immune system modulating effects in a large number of pharmacological tests. Diosgenin is also one of the important raw materials for the synthesis of steroidal drugs, and structural modification of diosgenin to obtain diosgenin derivatives can not only improve the solubility and dissolution, but also enhance their pharmacological effects. This paper reviews the synthetic reactions, pharmacological effects of diosgenin and its derivatives, aiming to provide detailed information for the further development and application of diosgenin, which is important to improve the utilization value of diosgenin.
Source: Food Science and Technology
DOI: 10.1590/fst.94521
Authors: Nannan HUANG, Dan YU, Junkai WU, Xiaowei DU
Institution: Heilongjiang University of Chinese Medicine
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $750
Awards: G336504766, G550395284
OpenAlex ID: W4200570540