Simultaneous Voltammetric Determination of Paracetamol and Ascorbic Acid Using Activated Glassy Carbon Electrode: Cyclic Voltammetry and Square Wave Voltammetry Study
Year: 2021
Type: article
Abstract: Simultaneous voltammetric determination of paracetamol (PA) and ascorbic acid (AA) at activated glassy carbon electrode (aGCE) using cyclic voltammetry (CV) and square wave voltammetry (SWV) was studied.The electrochemical responses of PA and AA were compared at bare (bGCE) and aGCE.The aGCE displayed excellent electrochemical catalytic activities and decreased the over-potential for simultaneous determination of PA and AA.It was found that the redox process at aGCE for both PA and AA is adsorption-controlled process.The linear range, limit of quantification (LOQ) and detection limit (LOD) of PA were found to be 10 to 100 µM; 0.517 µM and 0.155 µM, respectively.Similarly, the linear range, LOQ and LOD of AA were found to be 0.4 to 0.95 mM, 6.32 µM and 1.89 µM, respectively.The validity of the proposed method was checked by using commercial drug which contain different amount of PA and AA and satisfactory percent recoveries were obtained.
Source: Acta Chemica Iasi
Authors: Yared Shewarega, Dereje Yenealem, Fikadu Siyum
Institutions: Kebri Dehar University, University of Gondar
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4205820587