Study on the Nasogastric Tube Passage and the Stability of Active Ingredients in a Simple Suspension Method of Oral Drugs in Combination with Multiple Drugs
Year: 2021
Type: article
Abstract: In case of difficulty in oral drug administration to patients with dysphagia, the simple suspension method is useful for administering a drug by a nasogastric tube, and is used in many medical institutions. However, information on the simultaneous application of multiple drugs by the simple suspension method is insufficient. In this study, we used aspirin, clopidogrel sulfate, lansoprazole, atorvastatin calcium, and amlodipine besylate, which are commonly used in patients with cerebrovascular disease, to evaluate the suspensibility, nasogastric tube passability, and stability of the active ingredient in the simultaneous multiple suspension method. Under the conditions of four agents (excluding amlodipine besylate) and five agents, the entire suspension can be passed through the nasogastric tube by changing the nasogastric tube diameter or changing the suspending procedure, with no decreases in recovery of the active ingredient after passing through the nasogastric tube.
DOI: 10.5649/jjphcs.47.70
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4211222697