Work

MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape

Year: 2022

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2022.02.013

Authors: Sarah Naomi Olsen, Laura Godfrey, James P. Healy, Yoolim A. Choi, Yan Kai, Charles Hatton, Florian Perner, Elena L. Haarer, Behnam Nabet, Guo-Cheng Yuan, Scott A. Armstrong

Institutions: Boston Children's Hospital, Harvard University, Dana-Farber Cancer Institute, Universitätsmedizin Greifswald, Universität Greifswald, Fred Hutch Cancer Center, Icahn School of Medicine at Mount Sinai, Dana-Farber/Harvard Cancer Center

Language: English

Topic: Chromatin Remodeling and Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Cancer Institute

Awards: G1570399396, Targeting DOT1L for Degradation in MLL-rearranged Leukemia, G3357112437, Big Omics Data Engine 2 Supercomputer, SPORE in Myeloid Malignancies, G7457793036, COVID and Translational Science supercomputer (CATS)

OpenAlex ID: W4220698374

FWCI: 3.942

Cites: 68

Cited by: 67

Related to: 10