Get started
Work

A detailed review on the phytochemical profiles and anti-diabetic mechanisms of Momordica charantia

Year: 2022
Type: article
Abstract: exhibits its anti-diabetic effects via the suppression of MAPKs and NF-κβin pancreatic cells, promoting glucose and fatty acids catabolism, stimulating fatty acids absorption, inducing insulin production, ameliorating insulin resistance, activating AMPK pathway, and inhibiting glucose metabolism enzymes (fructose-1,6-bisphosphate and glucose-6-phosphatase). Reviewed literature was obtained from credible sources such as PubMed, Scopus, and Web of Science.
Source: Heliyon
DOI: 10.1016/j.heliyon.2022.e09253
Authors: Sunday Faith Oyelere, Oluwatobi Hezekiah Ajayi, Titilayo Eunice Ayoade, George Bueno Santana Pereira, Bolaji Charles Dayo Owoyemi, Ajibola Olaoluwa Ilesanmi, Olalekan Amos Akinyemi
Institutions: Universitat de Lleida, Georgia State University, Ladoke Akintola University of Technology, Universidade Federal de São Carlos, East Tennessee State University, University of Kentucky
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $1,950
OpenAlex ID: W4224217469
FWCI: 6.009
Cites: 141
Cited by: 49
Related to: 10