Surgical treatment of hydatid disease of central nervous system - our experien ce and review of the literature
Year: 2015
Type: article
Abstract: Introduction: Echinococcosis is a widespread parasitic disease of humans caused by the larval stages of Echinococcus granulosus.The involvement of CNS is relatively rare and therefore its clinical diagnosis is often difficult.Cerebral hydatid disease represents about 2-4% of all cases of echinococcosis, while the incidence of echinococcosis among space-occupying lesions of the brain varies between different countries and may reach 1.6-2.8%.The hydatid disease of the spine occurs in 1% of hydatidosis and is mostly located in the thoracic spine.Solitary affection of both the brain and the spine is an exception.Materials and methods: Eight patients with hydatid disease of CNS were surgically treated for a 10 years period.Six of them were with cerebral echinococcosis, in one case it is a primary echinococcus cyst and 2 patients with spinal hydatid diseasein one of the cases there is a rare cervico-occipital localization of the cyst.In all cases the diagnosis was made late and the patients were in serious overall condition and pronounced neurological deficit.Discussion: Cerebral hydatid disease is a rare type of space-occupying lesions of the brain.It occurs 2-3 times more common in children than in adults.In the majority of cases, cerebral echinococcosis is accompanied by lesions in lung or liver.Isolated affection is an exception.In a diagnostic term the cerebral hydatid cysts presents with characteristic features on preoperative cerebral CT scans and are therefore easily diagnosed.However, in many cases the diagnosis comes late, after exhaustion of adaptation capabilities of the brain.The reason for this must be observed in the absence of echinococcosis in differential diagnostic term of thinking mainly because of its rarity.Surgical resection is the therapy of choice in both the cerebral and spinal echinococcosis.Accurate preoperative diagnosis is essential, as intra-operative rupture of the cyst will result in spreading of the disease.
Source: Trakia Journal of Sciences
Authors: St. Valkanov, I. Chakarov, Ts. Popkharitov, A. Popkharitov, B. Chakarova, P. Chakarova, P. Valkanov, B. Petrov, I. Mindov
Institution: Trakia University
Language: English
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4242851986