Toxicogenomics Through the Eyes of Informatics: Conference Overview and Recommendations
Year: 2004
Type: article
Abstract: The availability of genome-scale DNA sequence information has radically altered life science research.Moreover, the human genome project has revolutionized the practice of biology and the potential of medicine.The field of toxicology will be greatly augmented by the application of the knowledge of genetics and its sister sciences.Consequently, researchers have entered a new area of specialty-toxicogenomics-the marriage of toxicology and genomics.Data generated by such research will impact many areas including health and environmental sciences.In addition, the science and health care communities will also be better able to identify a wide range of human health risks.However, to realize the potential of toxicogenomics, a global view of gene function and temporal and spatial regulations for all genes at different physiological or pathological states or developmental stages is paramount.The expanding field of bioinformatics offers the convergence of biological, mathematical, and computational platforms to better understand the effects of toxins on biological systems.Scientists using data developed by the modern advent of biotechnology need novel and efficient bioinformatics tools to monitor gene-environment interactions on a large scale.These bioinformatics platforms (hardware, software, portals, and models, for example) will allow the conversion of data into useful knowledge to prevent disease resulting from environmental exposures.
DOI: 10.1289/txg.6799
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $4,500
OpenAlex ID: W4243204548