Work

A Rare Homoisoflavonoid Cambodianol from Sansevieria roxburghiana

Year: 2013
Type: article
Abstract: Sansevieria roxburghiana (Family-Agavaceae), called Murva in Sanskrit and Hindi, Indian bowstring hemp in English is a herbaceous perennial plant with short fleshy stem and stout rootstock, occurring in eastern coastal region of India, as well as in Sri Lanka, Indonesia and tropical Africa 1,2 .In India, this plant has been traditionally used for several medicinal purposes.The whole plant is traditionally used as a cardiotonic, expectorant, febrifuge, purgative, tonic, in glandular enlargement and rheumatism [3][4][5] .The rhizomes are mucilaginous and used in consumptive complaints, long lasting chronic persistent coughs, for quick relief of common cough and cold, in ear pain, etc. 2,[5][6][7] .The juice of tender shoots is administered to children for clearing viscid phlegm from throats.The roots are used as febrifuge in snake bite and hemorrhoids 6,7 .The occurrence of steroidal saponins in the genus Sansevieria is well documented [8][9][10] .However, a survey of the literature showed that no chemical studies have been carried out on the constituents of Sansevieria roxburghiana (Agavaceae).We, herein, report the isolation of cambodianol (1) and lupeol (2) from the carbon tetrachloride soluble fraction of a methanol extract of S. roxburghiana.The 1 H NMR spectra were recorded using a Bruker AMX-400 (400 MHz) instrument and the spectra were referenced to the residual nondeuterated solvent signal.PTLC was carried out using Merck Si gel 60 F254 on glass plates (20 cm X 20 cm) at a thickness of 0.5 mm.TLC was conducted on normalphase Merck Si gel 60 F254 on glass plates and spots on TLC and PTLC plates were visualized under UV light at 254 nm as
Institution: University of Dhaka
Language: English
Subfield: Drug Discovery
Open Access status: diamond
OpenAlex ID: W4246469293
FWCI:
Cites: 3
Cited by: 2
Related to: 10