Work

Artificial selection reveals the role of transcriptional constraints in the maintenance of life history variation

Year: 2020

Type: paratext

Abstract: The trade-off between reproduction and self-maintenance is a cornerstone of life history theory, yet its proximate underpinnings are elusive. Here, we used an artificial selection approach to create replicated lines of Japanese quail (Coturnix japonica) that differ genetically in their reproductive investment. Whole transcriptome sequencing revealed that females from lines selected for high reproductive output show a consistent upregulation of genes associated with reproduction but a simultaneous downregulation of immune genes. Concordant phenotypic differences in immune function (i.e., specific antibody response against keyhole limpet hemocyanin) were observed between the selection lines, even in males who do not provide parental care. Our findings demonstrate the key role of obligate transcriptional constraints in the maintenance of life history variation. These constraints set fundamental limits to productivity and health in natural and domestic animal populations.

Source: Evolution Letters

DOI: 10.1002/evl3.v4.3

Authors: Pick, Joel L., Hatakeyama, Masaomi, Ihle, Kate E., Gasparini, Julien, Haussy, Claudy, Ishishita, Satoshi, Matsuda, Yoichi, Yoshimura, Takashi, Kanaoka, Masahiro M., Shimizu‐inatsugi, Rie, Shimizu, Kentaro K., Tschirren, Barbara

Institutions: University of Zurich, UNSW Sydney, University of Edinburgh, Functional Genomics Center Zurich, Centre National de la Recherche Scientifique, École Normale Supérieure - PSL, Université Pierre-et-Marie-Curie, Nagoya University, Kihara Institute for Biological Research, Yokohama City University, University of Exeter

Language: English

Topic: Animal Behavior and Reproduction

Subfield: Ecology, Evolution, Behavior and Systematics

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,500

Funders: National Science Foundation, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Universität Zürich, Japan Society for the Promotion of Science

Awards: G1193540627, G1694642594, G20659343, The evolution and evolutionary consequences of prenatal maternal effects – from genes to populations, Causes and consequences of prenatal maternal effects – from genes to populations, Elucidating the eco-evolutionary dynamics of variation within individuals, populations and species, Breeding systems and germline development – evolutionary genomic analysis using Arabidopsis relatives

OpenAlex ID: W4247121069

Cites: 57

Cited by: 1

Related to: 10