Work

Draft Genome Sequence of Escherichia coli Strain ATCC 23502 (Serovar O5:K4:H4)

Year: 2013

Type: article

Abstract: We report the 4.682-Mbp high-quality draft assembly of the Escherichia coli strain ATCC 23502 (serovar O5:K4:H4, also known as NCDC U1-41) genome. This uropathogenic strain, commonly referred to as E. coli K4, produces a glycosaminoglycan-like capsular polysaccharide with a backbone similar in structure to unsulfated chondroitin, a precursor to the nutraceutically and potentially pharmaceutically valuable compound chondroitin sulfate. Metabolic reconstruction of this genome will enable prediction of genetic engineering strategies leading to increased chondroitin production.

Source: Genome Announcements

DOI: 10.1128/genomea.00046-13

Authors: Brady F. Cress, Zachary R. Greene, Robert J. Linhardt, Mattheos A. G. Koffas

Institution: Rensselaer Polytechnic Institute

Language: English

Topic: Escherichia coli research studies

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funders: Rensselaer Polytechnic Institute, Weill Cornell Medical College

OpenAlex ID: W4249944486

FWCI: 0.948

Cites: 7

Cited by: 10

Related to: 10