Work

Evaluation of Cell‐Penetrating Peptides Using Microfluidic In Vitro 3D Brain Endothelial Barrier

Year: 2020

Type: article

Abstract: Front Cover: In article number 1900425, Hyun Jeong Oh, Seok Chung and co-workers reconstituted the 3D brain endothelial barrier in a microfluidic device with a hydrogel scaffold. The developed platform provides quantitative evaluation of the efficacy of cell-penetrating peptide (CPP) utilizing receptor-mediated transcytosis by various assays. The specific/non-specific transcytosis of CPP in the microfluidic platform is demonstrated and evaluated.

Source: Macromolecular Bioscience

DOI: 10.1002/mabi.202070011

Authors: Bohye Chung, Jaehoon Kim, Jiyoung Nam, Hyunho Kim, Yeju Jeong, Hui‐wen Liu, Youngkyu Cho, Yong Ho Kim, Hyun Jeong Oh, Seok Chung

Language: English

Topic: Barrier Structure and Function Studies

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4251525317

FWCI: 0.193

Cites:

Cited by: 5

Related to: 10