Discussion: Evaluation of Current Clinical Status and Future Directions in Non-Small Cell Lung Cancer
Year: 2009
Type: article
Abstract: Treatment of Operable DiseaseDr. Burnt: The only published trial in the United States that investigated platinum-containing adjuvant treatment for resected patients was from the Lung Cancer Study Group, which conducted a randomized trial in patients w ith stages II and IIIA large cell adenocarcinoma that had been re sected.Patients received either postoperative CAP che motherapy, which was cyclophosphamide, doxorubicin, and cisplalin.or no chemotherapy.Patients in the other arm received immunotherapy with BCG and levamisole.Survival in patients receiving chemotherapy was a median of 8 months longer, and cure rate at 5 years was about 10% higher.This group also studied stage I resected patients with CAP versus no further therapy and found no differ ence in survival.
Source: Oncology
DOI: 10.1159/000227115
Authors: Anthony Greco, Patrick B. Murphy, John D. Hainsworth, Kenneth R. Hande, David H. Johnson, Philip Bonomi, Hisanobu Niitani, Kunihiko Kobayashi, David H. Johnson, John D. Hainsworth, Russell DeVore, Kenneth R. Hande, Anthony Greco, Kiyoyuki Furuse, Martin Wolf, Christian Goerg, Konrad Goerg, Rudiger Pfab, Wolf Achterrath, Klaus Havemann, Nagahiro Saijo, James F. Bishop, Noriyuki Masuda, Masahiro Fukuoka, Kiyoyuki Furuse, Ulrich Gatzemeier, Joachim von Pawel, Reiner Laumen, Dieter K. Hossfeld, Renate Neuhauss, Martin Reck, Luigi Lenaz
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4252017283