Year: 2022
Type: article
Abstract: Kaposi's sarcoma (KS) is a rare, malignant, multilocular vascular disease originating from lymphatic endothelial cells that can primarily affect the skin and mucous membranes, but also the lymphatic system and internal organs such as the gastrointestinal tract, lungs or liver. Five epidemiological subtypes of KS with variable clinical course and prognosis are distinguished, with increased incidence in specific populations: (1) Classical KS, (2) Iatrogenic KS in immunosuppression, (3) Endemic (African) lymphadenopathic KS, (4) Epidemic, HIV-associated KS and KS associated with immune reconstitution inflammatory syndrome (IRIS), and (5) KS in men who have sex with men (MSM) without HIV infection. This interdisciplinary guideline summarizes current practice-relevant recommendations on diangostics and therapy of the different forms of KS. The recommendations mentioned in this short guideline are elaborated in more detail in the extended version of the guideline (online format of the JDDG).
DOI: 10.1111/ddg.14788
Authors: Stefan Esser, Helmut Schöfer, Christian Hoffmann, Johannes Claßen, Alexander Kreuter, Ulrike Leiter, Mark Oette, Jürgen C. Becker, Mirjana Ziemer, Franz Mosthaf, Judith Sirokay, Selma Ugurel, Anja Potthoff, Doris Helbig, Erhard Bierhoff, Thomas F. Schulz, Norbert H. Brockmeyer, Stephan Grabbe
Institutions: Essen University Hospital, University of Duisburg-Essen, Helios Dr. Horst Schmidt Kliniken Wiesbaden, Christian-Albrechts-Universität zu Kiel, University Hospital Schleswig-Holstein, Infektionsmedizinisches Centrum Hamburg, Witten/Herdecke University, HELIOS St. Elisabeth Klinik Oberhausen, Universitätsklinikum Tübingen, University of Tübingen, Krankenhaus der Augustinerinnen, German Cancer Research Center, Stiftung Universitätsmedizin Essen, University Hospital Leipzig, University Hospital Bonn, Ruhr University Bochum, University Hospital Cologne, Medizinische Hochschule Hannover, University Medical Center of the Johannes Gutenberg University Mainz
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,950
Funder: Andrew W. Mellon Foundation
OpenAlex ID: W4281634278