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LPCAT3 Inhibitors Remodel the Polyunsaturated Phospholipid Content of Human Cells and Protect from Ferroptosis

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Year: 2022
Type: article
Source: ACS Chemical Biology
DOI: 10.1021/acschembio.2c00317
Authors: Alex Reed, Taka-Aki Ichu, Natalia Milosevich, Bruno Melillo, Michael A. Schafroth, Yuka Otsuka, Louis Scampavia, Timothy P. Spicer, Benjamin F. Cravatt
Institution: Scripps Research Institute
Language: English

Topic: Lipid metabolism and biosynthesis
Subfield: Biochemistry
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute on Drug Abuse
Awards: Integrated Acoustic Transfer System for HTS Library Management, G120164892, G2336841923, HTS DrugĀ  Discovery Dispensers
OpenAlex ID: W4281794414
FWCI: 9.9
Cites: 42
Cited by: 161
Related to: 10
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