Iron deficiency in Russia heart failure patients. Observational cross-sectional multicenter study
Year: 2022
Type: article
Study design: Observational Study
Abstract: Aim To evaluate the prevalence of iron deficiency (ID) in Russian patients with heart failure (HF).Material and methods Iron metabolism variables were studied in 498 (198 women, 300 men) patients with HF. Data were evaluated at admission for HF (97 %) or during an outpatient visit (3 %). ID was determined according to the European Society of Cardiology Guidelines.Results 83.1 % of patients had ID; only 43.5 % of patients with ID had anemia. Patients with ID were older: 70.0 [63.0;79.0] vs. 66.0 years [57.0;75.2] (p=0.009). The number of patients with ID increased in parallel with the increase in HF functional class (FC). Among patients with ID, fewer people were past or current alcohol users (p=0.002), and a greater number of patients had atrial fibrillation (60.1 vs. 45.2 %, p=0.016). A multiple logistic regression showed that more severe HF (HF FC) was associated with a higher incidence of ID detection, whereas past alcohol use was associated with less pronounced ID. An increase in N-terminal pro-brain natriuretic peptide (NT-proBNP) by 100 pg/ml was associated with an increased likelihood of ID (odds ratio, 1.006, 95 % confidence interval: 1.002-1.011, p=0.0152).Conclusion The incidence rate of HF patients is high in the Russian Federation (83.1 %). Only 43.5 % of these patients had anemia. The prevalence of ID in the study population increased with increases in HF FC and NT-proBNP.
Source: Kardiologiia
Authors: V. Yu. Mareev, Yu. L. Begrambekova, Yu. V. Mareev, Zh. D. Kobalava, L. V. Karapetyan, S. A. Galochkin, E. R. Kazakhmedov, A. A. Lapshin, A. A. Garganeeva, E. A. Kuzheleva, A. А. Efremushkina, E. V. Kiseleva, O. L. Barbarash, T. B. Pecherina, A. S. Galyavich, Z. M. Galeeva, L. V. Baleeva, N. A. Koziolova, A. S. Veklich, D. V. Duplyakov, M. N. Maksimova, S. S. Yakushin, E. A. Smirnova, E. V. Sedykh, I. I. Shaposhnik, N. A. Makarova, A. A. Zemlyanukhina, V. V. Skibitsky, A. V. Fendrikova, A. V. Skibitsky, N. A. Spiropulos, E. M. Seredenina, Ya. A. Orlova, K. A. Eruslanova, Yu. V. Kotovskaya, O. N. Tkacheva, M. A. Fedin
Institutions: Lomonosov Moscow State University, Peoples' Friendship University of Russia, Tomsk National Research Medical Center, Institute of Cardiology, Altai State Medical University, Research Institute of Complex Problems of Cardiovascular Disease Russian Academy of Medical Sciences, Kazan State Medical University, Perm State Medical Academy, Samara State Medical University, Ryazan State Medical University named after Academician I.P. Pavlov, Chelyabinsk State Medical Academy, Municipal Autonomous Healthcare Institution, Kuban State Medical University, Pirogov Russian National Research Medical University
Language: Russian
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4282837313