Work

Sympathetic ophthalmia: A comprehensive update

Year: 2022

Type: review

Abstract: Sympathetic ophthalmia is a rare, bilateral, granulomatous, panuveitis following penetrating trauma or surgery to one eye. Clinical presentation commonly occurs within the first year of trauma occurrence but can be delayed by several years. It manifests as acute/chronic granulomatous uveitis with yellowish-white choroidal lesions or Dalen-Fuchs nodules. Initially, patients respond rapidly to corticosteroid therapy, but a majority require long-term use of corticosteroid-sparing agents to prevent recurrences. The purpose of this review is to elaborate on the current understanding of the pathophysiology, the importance of multimodal imaging in early diagnosis, and the role of newer immunomodulatory and biological agents in recalcitrant cases.

Source: Indian Journal of Ophthalmology

DOI: 10.4103/ijo.ijo_2363_21

Authors: Swapnil Parchand, Deepshikha Agrawal, Nikitha Ayyadurai, Aniruddha Agarwal, Anil Gangwe, Shashwat Behera, Priyavat Bhatia, Samyak Mulkutkar, Gulshan Barwar, Ramandeep Singh, Alok Sen, Manisha Agarwal

Institutions: Post Graduate Institute of Medical Education and Research, Cleveland Clinic Abu Dhabi, P. D. Hinduja Hospital and Medical Research Centre, Dr. Shroff’s Charity Eye Hospital

Language: English

Topic: Ocular Diseases and Behçet’s Syndrome

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4282943883

FWCI: 1.713

Cites: 86

Cited by: 53

Related to: 10