Year: 2022
Type: article
Abstract: BACKGROUND: In June 2019, the Bolivian Ministry of Health reported a cluster of cases of hemorrhagic fever that started in the municipality of Caranavi and expanded to La Paz. The cause of these cases was unknown. METHODS: We obtained samples for next-generation sequencing and virus isolation. Human and rodent specimens were tested by means of virus-specific real-time quantitative reverse-transcriptase-polymerase-chain-reaction assays, next-generation sequencing, and virus isolation. RESULTS: ). In survivors of CHHF, viral RNA was detected up to 170 days after symptom onset; CHAPV was isolated from a semen sample obtained 86 days after symptom onset. CONCLUSIONS: . (Funded by the Bolivian Ministry of Health and others.).
Source: New England Journal of Medicine
Authors: Roxana Loayza Mafayle, Maria E. Morales-Betoulle, Carla Romero, Caitlin M. Cossaboom, Shannon Whitmer, Carlos E. Alvarez Aguilera, Cinthia Avila Ardaya, Mirian Cruz Zambrana, Andrés Dávalos Anajia, Nelly Mendoza Loayza, Ana-Maria Montaño, Fernando L. Morales Alvis, Jimmy Revollo Guzmán, Sebastián Sasías Martínez, Gricel Alarcón De La Vega, Armando Medina Ramírez, Jhemis T. Molina Gutiérrez, Alex J. Cornejo Pinto, Renata Salas Bacci, Julia Brignone, Jorge Garcia, Arletta Añez, Jairo Mendez-Rico, Kleber Luz, Ariel Segales, Karen M. Torrez Cruz, Adolfo Valdivia-Cayoja, Brian R. Amman, Mary J. Choi, Bobbie-Rae Erickson, Cynthia Goldsmith, James C. Graziano, Allison Joyce, John D. Klena, Austin Leach, Jason H. Malenfant, Stuart T. Nichol, Ketan Patel, Tara Sealy, Trevor Shoemaker, Christina F. Spiropoulou, Alison Todres, Jonathan S. Towner, Joel M. Montgomery
Language: English
Topic: Viral Infections and Vectors
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Award: G7543494365
OpenAlex ID: W4282967560