Work

Diagnosis of the Primary Tumor Site in the Case of Liver Metastatic Carcinoma

Year: 2022

Type: article

Abstract: Immunohistochemical markers have been frequently utilized as a diagnostic tool in pathology to help in diagnosing malignancy of unknown primary sites. In previous cases, the immunohistological expression of cytokeratin 7 (CK7), Napsin A, and thyroid transcription factor-1 (TTF-1) has helped identify and diagnose primary malignancy as originating from the lung. This case report describes an elderly woman with a liver metastasis consistent with a lung primary and illustrates the utility and importance of tissue-specific markers as a diagnostic tool in the evaluation of unknown primary tumors.

Source: Cureus

DOI: 10.7759/cureus.26782

Authors: Mercedes Malone, Christopher Bray, Xiaolong Sean Liu

Institutions: University of Central Florida, HCA Healthcare

Language: English

Topic: Cancer Diagnosis and Treatment

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: HCA Healthcare