Work

Self-Assembly of DNA-Grafted Colloids: A Review of Challenges

Year: 2022

Type: review

Abstract: DNA-mediated self-assembly of colloids has emerged as a powerful tool to assemble the materials of prescribed structure and properties. The uniqueness of the approach lies in the sequence-specific, thermo-reversible hybridization of the DNA-strands based on Watson-Crick base pairing. Grafting particles with DNA strands, thus, results into building blocks that are fully programmable, and can, in principle, be assembled into any desired structure. There are, however, impediments that hinder the DNA-grafted particles from realizing their full potential, as building blocks, for programmable self-assembly. In this short review, we focus on these challenges and highlight the research around tackling these challenges.

Source: Micromachines

DOI: 10.3390/mi13071102

Authors: Manish Dwivedi, Swarn Lata Singh, Atul S. Bharadwaj, Vimal Kishore, Ajay Vikram Singh

Institutions: Banaras Hindu University, University of Allahabad, German Federal Institute for Risk Assessment (BfR)

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $2,094

Funder: Banaras Hindu University