Work

Daily online contouring and re-planning versus translation-only correction in neurovascular-sparing magnetic resonance-guided radiotherapy for localized prostate cancer

Year: 2022

Type: article

Abstract: Neurovascular bundle (NVB) and internal pudendal artery (IPA) sparing during magnetic resonance-guided radiotherapy (MRgRT) for prostate cancer aims for preservation of erectile function. Our present workflow involves daily online contouring and re-planning on a 1.5 T MR-linac, as alternative to conventional (rigid) translation-only corrections of the prostate. We compared planned dose for the NVB and IPA between strategies. Total planned dose was significantly lower with daily online contouring and re-planning for the NVB, but not for the IPA. For the NVB and IPA, the intrapatient difference between highest and lowest fraction dose was significantly smaller for the contouring and re-planning plans.

Source: Physics and Imaging in Radiation Oncology

DOI: 10.1016/j.phro.2022.09.002

Authors: Frederik R. Teunissen, Jochem R.N. van der Voort van Zyp, Eline N. de Groot-van Breugel, Helena M. Verkooijen, Ruud C. Wortel, Johannes C.J. de Boer

Institutions: University Medical Center Utrecht, Utrecht University

Language: English

Topic: Advanced Radiotherapy Techniques

Subfield: Radiation

Field: Physics and Astronomy

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,750