Year: 2022
Type: article
Study design: Case Report
Abstract: INTRODUCTION: Neuroendocrine carcinomas mainly affect the bronchopulmonary system and the gastrointestinal tract. Mammary localizations are rare. They represent less than 0.1 % of all breast cancers and less than 1 % of neuroendocrine tumors. CASE REPORT: Our case concerns a 50-year-old female patient, who has presented for one year with a rapidly evolving, hard, right breast nodule without associated adenopathy. DISCUSSION: The diagnosis of certainty is based on histological study, and more particularly on immunohistochemical study. Studies concerning this entity are rare and include a small number of cases. We have described a case of triple negative neuroendocrine carcinoma with a high proliferation index. The study of larger series will allow us to better understand their histogenesis as well as their evolutionary profile. CONCLUSION: The treatment of endocrine tumors of the breast is mainly surgical. The indications for chemotherapy and radiotherapy are the same as for other breast cancers.
Authors: Harrad Mouna, Watik Fedoua, Tangara Omar, Sami Zineb, Houssine Boufettal, Sakher Mahdaui, Naima Samouh
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,800
OpenAlex ID: W4296143232