Practical Recommendation of the Scientific Сommunity for Human Microbiome Research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgrowth in Adults
Year: 2022
Type: article
Abstract: Aim. To optimize the choice of treatment strategies by physicians and gastroenterologists to improve treatment and prevention of small intestinal bacterial overgrowth (SIBO) in adults. Key points. SIBO is a condition characterized by an increased amount and/or abnormal composition of the microbiota in the small intestine. Clinically, the syndrome is manifested by nonspecific gastroenterological complaints and the development of malabsorption syndrome. Most often, SIBO is associated with various chronic non- infectious diseases (both diseases of the gastrointestinal tract, and the cardiovascular system and the neuromuscular apparatus) and can affect the severity of their symptoms. Specific methods for diagnosing SIBO are the culture method and breath tests. The main approaches to the treatment of SIBO include the elimination of the underlying cause of its occurrence, the use of antibacterial drugs and adherence to dietary recommendations (elemental diet). Conclusion. Small intestinal bacterial overgrowth is common in patients with various diseases, but has non-specific manifestations, so proper diagnosis of this condition is required. SIBO therapy involves prescription of antibacterial agents, the most studied of which is the non-absorbable antibiotic rifaximin-α.
Authors: V. T. Ivashkin, I. V. Maev, D. I. Abdulganieva, O. P. Alekseeva, S. A. Alekseenko, O. Yu. Zolnikova, N. V. Korochanskaya, O. S. Medvedev, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, I. B. Khlynov, V. V. Tsukanov, O. S. Shifrin, K. V. Ivashkin, T. L. Lapina, R. V. Maslennikov, M. V. Fadeeva, A. I. Ulyanin
Institutions: Sechenov University, Russian University of Medicine, Kazan State Medical University, Privolzhsky Research Medical University, Far Eastern State Medical University, Kuban State Medical University, Lomonosov Moscow State University, Institute of Experimental Cardiology, National Medical Research Center of Cardiology, North-Western State Medical University named after I.I. Mechnikov, Ural State Medical University, Russian Academy of Sciences, Krasnoyarsk Scientific Center, Research Institute of Medical Problems of the North
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4296720482